With the score even at 4-4, Wofford's Trey Yunger opened the eighth with a single before advancing to second base on a balk. He then moved to third base following a sacrifice bunt and scampered home on a pitch missed by freshman backstop Asa Wilson.
Cole Palis and Ben Miller each hit their first home runs as Quakers, with Palis and Calvin Brown recording their first multi-hit games in a Penn uniform.
Owen Coady tossed four scoreless frames of relief, running his scoreless innings streak to 16 2/3, dating back to the 2021 season. He has 15 strikeouts this season and has issued just two walks.
The Quakers (3-4) now head to Charleston for a two-game series with the College of Charleston.
Wyatt Henseler continues to lead the offense, touting a .440 average with seven RBIs and a 1.340 OPS.